Our Specialties

No Burp

Imagine no more bloating, pain, or gurgles.

…Dr. Holmes is one of only a handful of physicians in the eastern U.S. providing “throatox” botox injections to help patients suffering from “no burp” — also known as Retrograde Cricopharyngeus Dysfunction (R-CPD).


We will continue to provide service to our No Burp patients through the end of September 2023, as we wind down our practice in Raleigh, NC. 

If you are seeking treatment and it is mid-September 2023, please still call to see if we have any openings to see you. 

After our Raleigh, NC practice closes in September 2023, Dr. Holmes will continue his work at the University of South Alabama. We hope you reach out to him at his new location.

What is “No Burp”?

While belching or burping is characterized as a day-to-day bodily function, for an unknown number of people, it’s a relief they never experience.

Instead, a big meal or carbonated beverage sets off a chain of gastric unpleasantries: bloating, searing pain in the esophagus, and excessive flatulence. And of course, the gurgling, a sound reminiscent of croaking frogs that seems to come from the throat.

Retrograde Cricopharyngeus Dysfunction (R-CPD) is a disorder where the cricopharyngeus muscle fails to relax to allow the upward passage of gas, and results in an inability to burp/belch.

How Can I Manage The Condition?

Many people in the No Burp community have found relief from botox injected into the cricopharyngeus muscle at the opening of the esophagus. Dr. Holmes is one of only a handful of physicians in the eastern U.S. providing Botox injections to no burp sufferers. Popularly known as “throatox,” these injections can provide significant relief from the symptoms of R-CPD.

Self Pay Options Available — Contact info@entandaudiology.com



3 o'clock Injection

Hear From Our Patients

You have CHANGED my LIFE
You have CHANGED my LIFE
Alex B.
Read More
This is the most amazing thing ever. I am crying tears of joy. For the first time in 40 years my stomach doesn’t hurt. You have changed my life. I cannot thank you enough.I go to bed comfortable and pain free. Thank you for listening, being practical, treating me rapidly, making the hospital experience fun. I send you all of the thank yous.